| 摘要 |
The invention relates to a method for production of compounds with formula (I), <IMAGE> and the physiologically acceptable salts thereof, where R1 is hydrogen or C1-4 alkyl, R2 is hydrogen or C1-4 alkyl, Alk is a methylene or ethylene group, R3 and R4 denote a C1-6 alkyl or alkoxyalkyl group, R5 is C1-4 alkyl, R6 is C1-13 alkyl or C5-8 cycloalkyl which can be substituted with C1-3 alkyl, and R7 is a halogen or hydrogen atom or C1-3 alkyl. The compounds with formula (I) reduce the intracellular calcium ion concentration by limiting the transmembranal calcium ion influx and they can be used in the treatment of cardiovascular disorders, such as hypertension.
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