发明名称 UREA-SUBSTITUTED IMIDAZOQUINOLINES, PHARMACEUTICAL PREPARATION AND METHOD FOR INDUCTION OF CYTOKINE BIOSYNTHESIS BASED ON THEREOF
摘要 FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to new urea-substituted imidazoquinolines of the formula (1): ^ wherein R, R1, R2 and n have values given in the description, and to pharmaceutical preparations based on these compounds. Proposed compounds possess effect of immunomodulators initiating biosynthesis of different cytokines. Also, invention relates to methods for treatment of different states, among them viral diseases and neoplastic pathologies. ^ EFFECT: improved method for induction, valuable properties of compounds. ^ 47 cl, 11 tbl, 142 ex
申请公布号 RU2265020(C2) 申请公布日期 2005.11.27
申请号 RU20010132570 申请日期 2000.06.08
申请人 发明人 KRUKS STEFEN L.;MERRILL BRAJON A.;RAJS MAJKL DZH.
分类号 A61K31/437;A61K31/4745;A61K31/5377;A61P1/02;A61P11/06;A61P27/16;A61P31/00;A61P31/10;A61P31/12;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D471/04 主分类号 A61K31/437
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