| 摘要 |
1428870 Cardenolide 5,19-acetals WARNERLAMBERT CO 2 Oct 1974 [8 Oct 1973] 42769/74 Heading C2U The invention comprises compounds of formula (wherein R 1 is optionally substituted glycosyl, and Ar is optionally substituted aryl or heteroaryl); and their preparation from the corresponding 5,14,19-triols by reaction with where R 2 is C 1 -C 6 alkyl, in the presence of an acidic catalyst and at a temperature of from -15‹ C. to the boiling point of the reaction mixture; optionally followed by alkylation, acylation or de-acylation of the sugar moiety. Oral and parenteral cardiotonic compositions comprise a compound I and a carrier.
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