Apparatus for treating an organ and related methods of use

摘要

A method of treatment may include advancing a medical device to a wall of an organ having a plurality of layers of tissue. The medical device may include an elongate tube having a proximal end and a distal end, a lumen extending therebetween, and an injector disposed within the lumen. The injector may be configured to deliver a substance to a location between first and second layers of tissue of the plurality of layers of tissue within the organ wall. In addition, the method may further include delivering the substance to the location, wherein, when delivered, the substance is configured to spatially separate a portion of the first and second layers of the tissue.

主权项

1. A method of treatment, comprising:
advancing a medical device to a wall of an organ of a patient, the wall having a plurality of layers of tissue including, from inside out, a first layer, a second layer, and a third layer containing a muscle, wherein the medical device comprises:
an elongate tube having a proximal end and a distal end and a lumen extending therebetween; andan injector disposed within the lumen of the elongate tube, the injector being configured to deliver a substance to one of a plurality of locations within the wall,wherein each of the plurality of locations is disposed between an innermost surface of the first layer and an outermost surface of the second layer, the first layer being a mucosal layer of the organ, the second layer being a submucosal layer of the organ; and delivering the substance to the plurality of locations to maintain a spatial separation between the first and second layers that modifies contraction of the muscle by inhibiting signal transduction for at least one month, wherein at least two of the plurality locations are discontinuous with one another.