| 发明名称 |
SULFONAMIDE DERIVATIVES AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES |
| 摘要 |
Disclosed are compounds of formula (I) which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein. |
| 申请公布号 |
PL2376480(T3) |
申请公布日期 |
2016.12.30 |
| 申请号 |
PL20060097956T |
申请日期 |
2009.12.04 |
| 申请人 |
|
发明人 |
BRUNCKO MILAN;DING HONG;DOHERTY GEORGE A.;ELMORE STEVEN W.;HASVOLD LISA;HEXAMER LAURA;KUNZER AARON R.;MANTEI ROBERT A.;MCCLELLAN WILLIAM J.;PARK CHANG H.;PARK CHEOL-MIN;PETROS ANDREW M.;SONG XIAOHONG;SOUERS ANDREW J.;SULLIVAN GERARD M.;TAO ZHI-FU;WANG GARY T.;WANG LE;WANG XILU;WENDT MICHAEL D. |
| 分类号 |
C07D405/12;A61K31/404;A61P35/00;C07D209/32;C07D211/96;C07D213/64;C07D215/20;C07D217/16;C07D231/56;C07D235/26;C07D249/04;C07D295/125;C07D295/14;C07D309/14;C07D401/12;C07D417/12 |
主分类号 |
C07D405/12 |
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