Anticancer agents of the anthracyclin family

摘要

Anthracyclin compounds of the general structure:;
are disclosed. In these compounds R1 is methyl, acetyl or hydroxyacetyl; R2—R5 and R10—R13 are independently H or methyl; R6 R7 and R8 are independently H, OH or OCH3; and n is zero or one. The compounds are useful for treating cancer.

主权项

1. A compound of formula: wherein R1 is chosen from methyl, acetyl and hydroxyacetyl; R2—R5 and R10 —R13 are independently chosen from H and methyl; R6 R7 and R8 are independently chosen from H, OH and OCH3; and n is one.