NOVEL PYRROLIDINE COMPOUND AND APPLICATION AS MELANOCORTIN RECEPTOR AGONIST

摘要

Provided are a novel pyrrolidine compound having melanocorin receptor agonist activity, a pharmacologically acceptable salt thereof, and pharmaceutical applications thereof. The present invention pertains to a pyrrolidine derivative represented by general formula (I) (in the formula, ring A represents a substitutable aryl group or the like; R1 represents a substitutable alkyl group; R2 represents a halogen atom or the like; R3 represents an alkyl group which may be substituted by a substitutable aryl group; and R4 is a hydrogen atom or the like; or R3 and R4 are terminally bonded to one another, and together with the nitrogen atoms bonded thereto, form substitutable nitrogen-containing aliphatic heterocycles which may partially contain double bonds), or a pharmacologically acceptable salt thereof.