N-BENZILAMIDE SI PROCEDEU DE OBTINERE A ACESTORA

摘要

Prepn. of N-benzylamide of formula (p)X-C6H4-CH2-NH-CO-R, where X is H, halogen or NO2, Y is a p-ClC6H4 radical is claimed. Acylation of benzylamides with acid chlorides is carried out in a modified Schotten-Baumann reaction. The reaction takes place in water-organic solvent (benzene) medium with hydrochloric acid incorporating an alkaline base (NaOH, etc.) present in the aqueous phase. The products are agents affecting the nervous system.