发明名称 Benzopyran derivatives and pharmaceutical compositions containing them
摘要 New benzopyran derivatives of general formula (I) in which: R1 denotes a hydrogen or halogen atom or a hydroxy, alkyloxy, nitro, amino, alkylsulphonamido, bis(alkylsulphonyl)amino, or acylamino radical, R denotes a radical of general formula: <IMAGE> in which A denotes a single bond or a methylene radical and R2 and R3 which may be identical or different, denote a hydrogen or halogen atom or a hydroxy, alkyl, alkyloxy, nitro, amino, alkylsulphonamido, bis(alkylsulphonyl)amino, acylamino, sulphamoyl or cyano radical, or form together, when they are adjacent, a methylenedioxy or ethylenedioxy radical, or alternatively R denotes a 2-oxo-2H-benzimidazolyl radical, and R' and R'' are identical and denote hydrogen atoms or alkyl radicals, their isomeric forms and their preparation. These new products are useful as antiarrhythmic and antifibrillating agents. <IMAGE> (I)
申请公布号 US4994470(A) 申请公布日期 1991.02.19
申请号 US19900465448 申请日期 1990.01.16
申请人 RHONE-POULENC SANTE 发明人 BARREAU, MICHEL;HARDY, JEAN-CLAUDE;RENAULT, CHRISTIAN
分类号 A61K31/443;A61K31/445;A61P9/06;C07D405/06;C07D405/14 主分类号 A61K31/443
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