发明名称 |
Methods for detection and treatment of disease using a glycosyltransferase |
摘要 |
The present invention relates to the prevention and treatment of a disease, preferably brain cancer, by administration of an isolated DNA molecule comprising a gene encoding a protein having glycosyltransferase activity to a cell involved in the disease which is preferably a glioblastoma cell. A method of treating brain cancer is provided in which a tumor cell is transfected either ex vivo or in vivo with a composition comprising a DNA molecule that encodes a protein having glycosyltransferase activity resulting in inhibition of the growth or function of that cell.
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申请公布号 |
US6566060(B1) |
申请公布日期 |
2003.05.20 |
申请号 |
US19990450195 |
申请日期 |
1999.11.29 |
申请人 |
CHICAGO INSTITUTE OF NEUROSURGERY AND NEURORESEARCH |
发明人 |
MOSKAL JOSEPH R.;YAMAMOTO HIROTAKA |
分类号 |
A61K48/00;C12N9/10;(IPC1-7):C12Q1/48;C07H21/02;C07H21/04;C07K14/00 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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