发明名称 Verfahren zur Herstellung von Sulfonamidderivaten
摘要 <p>Clear, injectable compn. comprising a mixture of:- (1) aq. soln. of a water-sol. salt of a sulphonamide, prefd. cpds. being: 5,6-dimethoxy-4-sulphanilamidopyrimidine; 3,4-dimethyl-5-sulphanilamidoisoxazole; 5-methyl-3,-sulphanilamidoisoxazole; 2,4-dimethoxy-6-sulphanilamidopyrimidine (A); 4,6-dimethyl-2-sulphanilamidopyrimidine; (2) soln. of a basic sulphonamide-potentiator in a suitable org. water-miscible solvent, prefd. cpds. (I) R1 = H, lower alkyl R2 = aryl 2,4-diamino-5-(3,4-dimethoxybenzyl)-pyrimidine -(3,4,5-trimethoxybenzyl)- -(3,4,6-trimethoxybenzyl)- -(3,4-dimethyl-6-methylbenzyl)- (B) -(4-chlorobenzyl)-6-ethylpyrimidine. Esp. useful in veterinary practice. Ensure correct propns. of sulphonamide and potentiator.</p>
申请公布号 CH544053(A) 申请公布日期 1973.11.15
申请号 CH19730002809 申请日期 1966.05.09
申请人 F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT 发明人 KLAEUI,HEINRICH,DR.;REHM,WALTER,DR.
分类号 A61K9/08;A61K31/635;A61K45/08;A61K47/10;A61K47/18;A61K47/20;A61K47/22;(IPC1-7):C07C143/72;C07D85/24;C07D51/44 主分类号 A61K9/08
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