发明名称 PROCEDIMIENTO PARA LA PREPARACION DE ACIDOS 4-(4-BIFENI- LIL)-BUTIRICOS Y SUS ESTERES.
摘要 <p>Title cpds. of formula (I): where A = CH2, CHOH or CO; R1 = H or hal, or (if R2 and R3 = H) ME; R3 = H) Me; R2 = H, hal, CN, NO2, NH2, or (1-4C) NH acyl; R3 = H or hal; R4 = (1-4C) alkyl; and at least one of R1-R3 = H, including salts, esters, and lactones of (I), are of use as anti-phlogistics. (I) are prepd. e.g., A = CO, by condensing a biphenyl with a succinic halide or anhydride and a Lewis acid; A = CH2 by reducing I (A = CO or CHOH) and other unsatd. analogues; A = CHOH by selective, partial redn. of I(A = CO).</p>
申请公布号 ES406125(A1) 申请公布日期 1975.08.01
申请号 ES19250004061 申请日期 1972.08.26
申请人 KARL THOMAE G.M.B.H. 发明人
分类号 A61K31/19;C07C45/46;C07C49/813;C07C53/19;C07C57/58;C07C59/56;C07C59/88;C07C69/76;C07C205/56;(IPC1-7):07C/;61K/ 主分类号 A61K31/19
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