| 摘要 |
NEW MATERIAL:The compound of formula I (R1 is H, lower alkyl, tetrahydropyranyl, etc.; R2 and R3 are H, halogen, hydroxy, lower alkonoyloxy, etc.; R4 is H or halogen; X is group of formula II, formula III, hydroxymethyl, formyl, etc.) and its salt. EXAMPLE:1-Hydroxy-6-(1-pyrrolo)carbonyl-3,5-dioxatricyclo[6.3.0.0<4.9> ]undeca-6,10- dien-2-one. USE:An antitumor agent. PREPARATION:The compound of formula I can be produced e.g. by suspending a compound of formula IV in a solvent such as acetonitrile and reacting with 1,4-dichloro-1,4-dimethoxybutane in the presence of a molecular sieve or an ion exchange resin.
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