发明名称 |
Interfacing capillary electrophoresis to a mass spectrometer via an impactor spray ionization source |
摘要 |
A mass spectrometer is disclosed comprising a separation device arranged and adapted to emit an eluent over a period of time. The separation device preferably comprises a Capillary Electrophoresis (“CE”) separation device. The mass spectrometer further comprises a nebuliser and a target. Eluent emitted by the separation device is nebulised, in use, by the nebuliser wherein a stream of analyte droplets are directed to impact upon the target so as to ionise the analyte to form a plurality of analyte ions. |
申请公布号 |
US9618488(B2) |
申请公布日期 |
2017.04.11 |
申请号 |
US201514832083 |
申请日期 |
2015.08.21 |
申请人 |
Micromass UK Limited |
发明人 |
Bajic Stevan |
分类号 |
H01J49/00;G01N30/72;G01N27/447;H01J49/16;G01N27/62;H01J49/04;H01J49/10 |
主分类号 |
H01J49/00 |
代理机构 |
Diederiks & Whitelaw, PLC |
代理人 |
Diederiks & Whitelaw, PLC |
主权项 |
1. A mass spectrometer comprising:
a separation device arranged and adapted to emit an eluent over a period of time, wherein said separation device comprises either: (i) a Capillary Electrophoresis (“CE”) separation device; (ii) a Capillary Electrochromatography (“CEC”) separation device; (iii) a substantially rigid ceramic-based multilayer microfluidic substrate (“ceramic tile”) separation device; or (iv) a supercritical fluid chromatography separation device; a nebuliser and; a target; wherein said eluent emitted by said separation device is nebulised, in use, by said nebuliser wherein a stream of analyte droplets are directed to impact upon said target so as to ionise said analyte to form a plurality of analyte ions. |
地址 |
Wilmslow GB |