摘要 |
Disclosed are prophylactic and therapeutic methods, as well as dosing regimens and medicaments for use in preventing chronic disease, for treating acute or long-term inflammatory-mediated conditions in affected or at-risk subjects, and for stabilizing one or more components of the mammalian extracellular matrix. Also disclosed are pharmaceutical compositions and topical formulations thereof that include multiple, phytochemically-active, nutraceutical compounds, and that possess potent anti-inflammatory and extracellular matrix-stabilizing properties both in vitro and in vivo. |
主权项 |
1. A method for reducing inflammation in a mammalian tissue, or ameliorating at least one symptom thereof, the method comprising: directly administering to the mammalian tissue, an effective amount of an aqueous composition comprising a) one or more catechins, catechin derivatives, or catechin analogs, agonists, or antagonists thereof; b) one or more curcuminoids, curcuminoid derivatives, or curcuminoid analogs, agonists, or antagonists thereof; c) one or more isothiocyanates, isothiocyanate derivatives, or isothiocyanate analogs, agonists, or antagonists thereof; d) one or more stilbenoids, stilbenoid derivatives, or stilbenoid analogs, agonists, or antagonists thereof; e) at least one therapeutic essential oil; f) tetrahydropiperine; and g) at least one compound selected from the group consisting of broccoli seed oil, mustard seed oil, wintercress oil, watercress oil, wintercress seed, watercress seed, and broccoli seed powder, for a time sufficient to reduce inflammation in the mammalian tissue, or to ameliorate the at least one symptom thereof. |