发明名称 |
METHOD OR KIT FOR DETERMINING LUNG CANCER DEVELOPMENT |
摘要 |
Disclosed herein is a method of determining whether a subject having or is at risk of developing lung cancer. The presence of the SNP locus of rs193100333, which corresponds to a mutation on YAP1 protein with a substitution of an arginine to a tryptophan at position 331, indicates the subject has or is at risk of developing lung cancer. Accordingly, also disclosed herein is a kit for facilitating the detection of the SNP locus of rs193100333. |
申请公布号 |
US2017081727(A1) |
申请公布日期 |
2017.03.23 |
申请号 |
US201615272442 |
申请日期 |
2016.09.22 |
申请人 |
National Taiwan University |
发明人 |
LI Ker-Chau;HO Bing-Ching;YU Sung-Liang;CHANG Gee-Chen;CHEN Hsuan-Yu;YANG Pan-Chyr |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
1. A method of determining whether a subject has or is at risk of developing lung cancer, comprising:
obtaining a biological sample from the subject; extracting DNA from the biological sample; and detecting the presence or absence of a single nucleotide polymorphism (SNP) locus of rs193100333 in the extracted DNA; wherein the presence of the SNP locus of rs193100333 indicates the subject has or is at risk of developing lung cancer. |
地址 |
Taipei TW |