发明名称 METHOD OR KIT FOR DETERMINING LUNG CANCER DEVELOPMENT
摘要 Disclosed herein is a method of determining whether a subject having or is at risk of developing lung cancer. The presence of the SNP locus of rs193100333, which corresponds to a mutation on YAP1 protein with a substitution of an arginine to a tryptophan at position 331, indicates the subject has or is at risk of developing lung cancer. Accordingly, also disclosed herein is a kit for facilitating the detection of the SNP locus of rs193100333.
申请公布号 US2017081727(A1) 申请公布日期 2017.03.23
申请号 US201615272442 申请日期 2016.09.22
申请人 National Taiwan University 发明人 LI Ker-Chau;HO Bing-Ching;YU Sung-Liang;CHANG Gee-Chen;CHEN Hsuan-Yu;YANG Pan-Chyr
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method of determining whether a subject has or is at risk of developing lung cancer, comprising: obtaining a biological sample from the subject; extracting DNA from the biological sample; and detecting the presence or absence of a single nucleotide polymorphism (SNP) locus of rs193100333 in the extracted DNA; wherein the presence of the SNP locus of rs193100333 indicates the subject has or is at risk of developing lung cancer.
地址 Taipei TW