Ensayo de acondicionamiento físico y métodos para reducir la resistencia del VIH a la terapia
摘要
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protease inhibitor. The present invention also provides a method of administering a therapeutic compound that reduces the chances of the emergence of drug resistance in therapy.
申请公布号
ES2604662(T3)
申请公布日期
2017.03.08
申请号
ES20100179052T
申请日期
1999.06.23
申请人
The United States of America, represented by the Secretary, Department of Health and Human Services;The Board Of Trustees Of The UniversityOf Illinois
发明人
Erickson, John W.;Gulnik, Sergei V.;Mitsuya, Hiroaki;Ghosh, Arun K.