Systems and methods for evaluating cardiac therapy

摘要

Systems and methods are described herein for assisting a user in evaluation of cardiac therapy. The systems and methods may monitor electrical activity of a patient using external electrode apparatus to provide baseline electrical heterogeneity information and therapy electrical heterogeneity information. The electrical heterogeneity information may be used to generate surrogate hemodynamic information.

主权项

1. A system for use in evaluation of cardiac therapy comprising:
electrode apparatus comprising a plurality of external electrodes configured to be located proximate tissue of a patient, wherein the plurality of electrodes comprises two or more left external electrodes configured to be located proximate the left side of the patient; and computing apparatus coupled to the electrode apparatus and configured to:
monitor baseline electrical activity using the plurality of external electrodes,monitor therapy electrical activity using the plurality of external electrodes during delivery of pacing therapy using a selected pacing configuration,generate electrical heterogeneity information representative of at least one of mechanical cardiac functionality and electrical cardiac functionality for each of the baseline electrical activity and the therapy electrical activity, wherein the electrical heterogeneity information comprises:
a global metric based on the electrical activity monitored by the plurality of external electrodes, andat least one local metric based on the electrical activity monitored by the two or more left external electrodes, andgenerate surrogate hemodynamic response information representative of the hemodynamic response to the pacing therapy delivered using the selected pacing configuration based on the electrical heterogeneity information for each of the baseline electrical activity and the therapy electrical activity.