发明名称 |
METHODS FOR STEM CELL TRANSPLANTATION |
摘要 |
The present disclosure provides methods of hematopoietic stem cell transplantation (HSCT). In particular, the present disclosure provides a method of HSCT using a combination of an in-vivo T-cell depletion method, with an ex-vivo method of γδ T cell expansion and αβ T cell depletion. The in-vivo T-cell depletion method depletes (in-vivo) the alloreactive T cells that would otherwise increase the risk of GvHD. |
申请公布号 |
WO2017035375(A1) |
申请公布日期 |
2017.03.02 |
申请号 |
WO2016US48738 |
申请日期 |
2016.08.25 |
申请人 |
THE UAB RESEARCH FOUNDATION |
发明人 |
LAMB, Lawrence S.;MINEISHI, Shin;SAAD, Ayman |
分类号 |
A61K35/14;A61K35/17;A61K35/28;A61P37/06;C12N5/02 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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