Methods and systems for delivering prostheses using rail techniques

摘要

Exemplary embodiments provide methods and systems for delivering a prosthesis to a target location in a lumenal system of a patient. At least one tether is secured proximate the target location to serve as a rail, and a prosthesis is advanced along the rail to the target location and secured in place. Exemplary methods and systems provide for repair of the mitral and tricuspid valves, as well as abdominal aortic aneurysms, stomach valves, fallopian tubes and the pulmonary system, among others. Also disclosed are various prostheses suitable for use with the disclosed methods and systems.

主权项

1. A method for treating a lumenal anatomical location, comprising:
a) advancing a distal region of a delivery catheter proximate a target location in a patient's lumenal system; b) dispensing a penetrating member from the delivery catheter proximate the target location; c) advancing the penetrating member through a first portion of lumenal tissue proximate the target location to define a first passage; d) advancing an end of a first tether through the first passage, the first tether having a first anchor disposed at the end thereof; e) advancing the first tether through the first passage until the first anchor bears against tissue proximate the first passage; f) disposing a prosthesis over the first tether; and g) advancing the prosthesis over the first tether to a position proximate the target location; and h) installing the prosthesis at the target location, wherein the prosthesis is compliant and conforms to the shape and the anatomy of the target location.