Production of para-propylbenzaldehyde

摘要

The present invention is a process for preparing a 4-alkylbenzaldehyde (para-alkylbenzaldehyde). An alkylbenzene, solvated in a solvent comprising at least one aliphatic solvent having in the range of 3 to 15 carbons, is reacted with carbon monoxide, in the presence of an aluminum halide and a hydrogen halide acid. Disproportionation is reduced and proportion of para-alkyl-benzaldehyde is increased with respect to other methods.

主权项

1. A process comprising:
A) adding to a reactor an alkylbenzene, aluminum halide, and at least one aliphatic hydrocarbon solvent having in a range of 3 to 15 carbons; B) cooling contents of the reactor to one or more temperatures in a range of 0 to −50° C.; C) adding to the reactor an amount of hydrogen halide acid sufficient to charge the reactor to a pressure in a range of about 25 psig to about 200 psig; D) adding to the reactor an amount of carbon monoxide sufficient to charge the reactor to a pressure in a range of about 200 psig to about 2000 psig; and E) maintaining a reaction temperature at one or more temperatures in a range of about −50° C. to about 20° C.; thereby synthesizing a 4-alkylbenzaldehyde.