Itch suppression by fucoxanthin

摘要

The present invention provides a method of suppressing mast cell differentiation and/or itch in the skin of a subject, comprising topically administering to the skin in need thereof an effective amount of fucoxanthin or a derivative thereof.

主权项

1. A method of suppressing mast cell differentiation in the skin of a subject, comprising topically administering to the skin in need thereof an effective amount of fucoxanthin, fucoxanthinol, amarouciaxanthin A, a monoester of fucoxanthin selected from esters with amino acids, esters with carboxylic acids and salts thereof, esters with inorganic acids and salts thereof, fatty acid esters with highly unsaturated fatty acids, unsaturated fatty acids, and saturated fatty acids, a diester of fucoxanthin having the same or different ester groups, or a glycoside.