发明名称 |
Tricyclic compound |
摘要 |
The present invention provides a compound having a superior serotonin 5-HT2C receptor activating action.;The present invention relates to a compound represented by the formula (1);
wherein
ring A is an aromatic carbocycle optionally having substituent(s) or an aromatic heterocycle optionally having substituent(s),X is —N(R1)—, —O— or the like,when ring A is an aromatic carbocycle optionally having substituent(s), then R1 is a hydrogen atom, an alkyl group optionally having substituent(s), or the like, andwhen ring A is an aromatic heterocycle optionally having substituent(s), then R1 is a hydrogen atom, an alkyl group optionally having substituent(s), a cycloalkyl group optionally having substituent(s), or the like,is a single bond or a double bond, andn is an integer of 0, 1 or 2,or a salt thereof. |
申请公布号 |
US9556200(B2) |
申请公布日期 |
2017.01.31 |
申请号 |
US201314381347 |
申请日期 |
2013.03.06 |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
Kusumoto Tomokazu;Sasaki Shigekazu;Maezaki Hironobu |
分类号 |
A61K31/55;C07D487/06;C07D495/06;C07D491/06 |
主分类号 |
A61K31/55 |
代理机构 |
Wenderoth, Lind & Ponack, L.L.P. |
代理人 |
Wenderoth, Lind & Ponack, L.L.P. |
主权项 |
1. A compound represented by the formula (1)wherein
ring A is benzene optionally having substituent(s), X is —N(R1)—, R1 is a hydrogen atom, an alkyl group optionally having substituent(s), a cycloalkyl group optionally having substituent(s), an alkylcarbonyl group optionally having substituent(s), an arylcarbonyl group optionally having substituent(s), an alkoxycarbonyl group optionally having substituent(s), or an alkylsulfonyl group optionally having substituent(s), is a single bond, and n is 0, or a salt thereof. |
地址 |
Osaka JP |