| 发明名称 | Rapid detection of the “high virulent” ST-17 clone of group B <i>streptococcus</i> | ||
| 摘要 | The present invention relates to polynucleotides enabling the rapid, simple and specific detection of Group B Streptococcus highly-virulent ST-17 clones.;The present invention also relates to the polypeptides encoded by said polynucleotides, as well as to antibodies directed or raised against said polypeptides.;The present invention also relates to kits and methods for the specific detection of Group B Streptococcus highly-virulent ST-17 clones, using the polynucleotides, the polypeptides or the antibodies according to the invention. | ||
| 申请公布号 | US9551039(B2) | 申请公布日期 | 2017.01.24 |
| 申请号 | US201414254051 | 申请日期 | 2014.04.16 |
| 申请人 | INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE PARIS DESCARTES;ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS | 发明人 | Poyart Claire;Lamy Marie-Cecile;Dramsi Shaynoor;Sauvage Elisabeth;Glaser Philippe;Trieu-Cuot Patrick |
| 分类号 | C12Q1/68 | 主分类号 | C12Q1/68 |
| 代理机构 | Law Office of Salvatore Arrigo and Scott Lee, LLP | 代理人 | Law Office of Salvatore Arrigo and Scott Lee, LLP |
| 主权项 | 1. A method for the in vitro detection of a high-virulence group B streptococcus strain of the ST-17 clone comprising: providing a biological sample comprising nucleic acid; hybridizing the nucleic acid of the biological sample with a nucleic acid molecule that hybridizes to a nucleotide sequence consisting of the S10 nucleotide sequence of SEQ ID NO:5, the S11a nucleotide sequence of SEQ ID NO: 13, or the S11b nucleotide sequence of SEQ ID NO: 15, or the complements thereof; and detecting the presence or absence of the ST-17 clone by detecting the presence or absence of the S10, S11a or S11b nucleotide sequence or the complement thereof in the nucleic acid of the biological sample. | ||
| 地址 | Paris FR | ||