发明名称 |
Imidazotriazinone compounds |
摘要 |
The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans. |
申请公布号 |
US9540380(B2) |
申请公布日期 |
2017.01.10 |
申请号 |
US201414334073 |
申请日期 |
2014.07.17 |
申请人 |
Ironwood Pharmaceuticals, Inc. |
发明人 |
Chesworth Richard;Koenig Gerhard;Ripka Amy;Shapiro Gideon |
分类号 |
C07D487/04;A61K31/53 |
主分类号 |
C07D487/04 |
代理机构 |
McCarter & English, LLP |
代理人 |
McCarter & English, LLP ;Barbic Andrej |
主权项 |
1. (+)-2-((3,4-trans)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-7-(tetrahydro-2H-pyran-4-yl)imidazo[5,1-f][1,2,4]triazin-4(3H)-one or a pharmaceutically acceptable salt thereof. |
地址 |
Cambridge MA US |