发明名称 Imidazotriazinone compounds
摘要 The present invention provides imidazotriazinone compounds which are inhibitors of phosphodiesterase 9. The present invention further provides processes, pharmaceutical compositions, pharmaceutical preparations and pharmaceutical use of the compounds in the treatment of PDE9 associated diseases or disorders in mammals, including humans.
申请公布号 US9540380(B2) 申请公布日期 2017.01.10
申请号 US201414334073 申请日期 2014.07.17
申请人 Ironwood Pharmaceuticals, Inc. 发明人 Chesworth Richard;Koenig Gerhard;Ripka Amy;Shapiro Gideon
分类号 C07D487/04;A61K31/53 主分类号 C07D487/04
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP ;Barbic Andrej
主权项 1. (+)-2-((3,4-trans)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-7-(tetrahydro-2H-pyran-4-yl)imidazo[5,1-f][1,2,4]triazin-4(3H)-one or a pharmaceutically acceptable salt thereof.
地址 Cambridge MA US
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