| 摘要 |
The present invention is directed to N-acylalkyl prodrugs of nitrogen-containing multi- tyrosine kinase inhibitors. The present invention is further directed to compositions comprising compounds of the invention. Finally, the present invention is directed to methods of treating eye conditions including, but not limited to, diabetic background retinopathy, diabetic macular edema, diabetic proliferative retinopathy, diabetic macular edema with proliferative retinopathy, proliferative fibrovascular disease, diabetic macular edema with proliferative fibrovascular disease, retinopathy of prematurity, dry macular degeneration, dry macular degeneration with drusen and wet macular degeneration, using compounds and compositions of the invention. |
