| 发明名称 |
COMPOUNDS AND METHOD FOR TREATING PARP1-DEFICIENT CANCERS |
| 摘要 |
Disclosed are compounds and a method of treating cancer that is PARP1-deficient compared to a wild-type form of the same cancer, the method involving administering an effective amount of a compound selected from and, in which ring A1, ring A2, Q, R1?-R8?, m, n, o, and p are as defined herein. |
| 申请公布号 |
WO2015112739(A9) |
申请公布日期 |
2016.10.20 |
| 申请号 |
WO2015US12493 |
申请日期 |
2015.01.22 |
| 申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
MYUNG, Kyungjae;CHOI, Yong Jun;ZHANG, Yongliang;MALONEY, David;ROHDE, Jason;BOXER, Matthew;BANTUKALLU, Ganesha Rai;XIA, Menghang;HUANG, Ruili;SMITH, Stephanie N. |
| 分类号 |
A61K31/517;A61K31/5377;A61P35/00;C07D239/94 |
主分类号 |
A61K31/517 |
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