发明名称 Methods and compositions for diagnosis and prognosis of renal injury and renal failure
摘要 The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Cellular tumor antigen p53 and optionally one or more biomarkers selected from the group consisting of Tumor necrosis factor receptor superfamily member 10B, Cadherin-16, Caspase-9, Bcl2 antagonist of cell death, Caspase-1, Cadherin-1, Poly [ADP-ribose] polymerase 1, Cyclin-dependent kinase inhibitor 1, Cadherin-5, Myoglobin, Apolipoprotein A-II, Mucin-16, Carcinoembryonic antigen-related cell adhesion molecule 5, and as diagnostic and prognostic biomarker assays in renal injuries.
申请公布号 EP2894473(B1) 申请公布日期 2016.09.21
申请号 EP20150150059 申请日期 2010.08.27
申请人 ASTUTE MEDICAL, INC. 发明人 ANDERBERG, JOSEPH;GRAY, JEFF;MCPHERSON, PAUL;NAKAMURA, KEVIN;KAMPF, JAMES PATRICK
分类号 G01N33/53;G01N33/68;G01N33/92 主分类号 G01N33/53
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