发明名称 ADMINISTRATION OF AN ANTI-ACTIVIN-A COMPOUND TO A SUBJECT
摘要 The present invention relates to methods of treating ovarian cancer in a subject by administering to the subject by evaluating the subject's expression levels of specific biomarkers or angiogenic an anti-activin-A compound, such as an anti-activin-A antibody or an activin-A-binding receptor. In some embodiments, at least two compounds are administered to the subject, where the first compound is an anti-activin A compound, and the second compound is a chemotherapeutic compound, for example capecitabine. The invention further relates to methods of identifying subjects for treatment factors.
申请公布号 EP2951205(A4) 申请公布日期 2016.09.07
申请号 EP20140746114 申请日期 2014.02.03
申请人 SANTA MARIA BIOTHERAPEUTICS, INC.;AMGEN INC. 发明人 HAN, HUIQUAN;HAQQ, CHRISTOPHER, MICHAEL;CIECHANOVER, ISAAC;ZHOU, XIAOLAN;LU, JOHN, ZHAO-NIAN
分类号 C07K16/26;A61K31/395;A61K31/704;A61K31/7068;A61K38/17;A61K39/00;A61K39/395;A61K45/06;C07K16/00;C07K16/22 主分类号 C07K16/26
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