发明名称 |
A TELOMERASE ENCODING DNA VACCINE |
摘要 |
The invention provides a nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of telomerase catalytic activity and of a nucleolar localization signal. The construct is useful triggering an immune response in a subject, against cells that overexpress telomerase, preferably dysplasia cells or tumor cells. |
申请公布号 |
EP3062824(A1) |
申请公布日期 |
2016.09.07 |
申请号 |
EP20140790592 |
申请日期 |
2014.10.28 |
申请人 |
INVECTYS |
发明人 |
LANGLADE DEMOYEN, PIERRE;WAIN-HOBSON, SIMON;HUET, THIERRY;LIARD, CHRISTELLE;PLIQUET, ELODIE |
分类号 |
A61K48/00;C12N9/12;C12N15/62 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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