发明名称 |
METHOD OF ENHANCING THE BIODISTRIBUTION AND TISSUE TARGETING PROPERTIES OF THERAPEUTIC CeO2 PARTICLES VIA NANO-ENCAPSULATION AND COATING |
摘要 |
The present invention provides methods and liposomal compositions useful in therapeutics, and diagnosis, prognosis, testing, screening, treatment and/or prevention of various disease conditions. The present invention provides imaging methods for various conditions. The present invention is a multi-layered drug delivery pathway, inclusive of nanoparticle liposomal formulations and mechanisms of localized action via unzipping upon delivery to the affected tissue site. The nano-encapsulation methodology allows maximization of a potent antioxidant's biocompatibility, increased target cell penetration and uptake, reduced off-target effects and retention of high anti-oxidative activity for promising therapeutic potential. |
申请公布号 |
EP2968148(A4) |
申请公布日期 |
2016.08.31 |
申请号 |
EP20140769574 |
申请日期 |
2014.03.14 |
申请人 |
PEROXYIUM, INC., DELAWARE C CORP. |
发明人 |
LEITER, JAMES;GILLMOR, SUSAN;JEREMIC, ALEKSANDAR;VERT-WONG, EKATERINA;FAIRBROTHERS, GREGG |
分类号 |
A61K9/51;A61K33/24 |
主分类号 |
A61K9/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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