ENHANCED TREATMENT REGIMENS USING PI3K INHIBITORS

摘要

The present invention provides for methods and pharmaceutical compositions comprising inhibitors of phosphatidylinositol 3-kinases (PI3Ks). In some aspects, the invention provides for treatment regimens resulting in enhanced treatment efficacy and better tolerability. In other aspects, the invention provides for methods of treatment and treatment regimens comprising combination of a phosphatidylinositol 3-kinase (PI3Ks) inhibitor and an estrogen receptor antagonist.