Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of Ack1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new Ack1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I through IV are disclosed.
申请公布号
EP3030241(A1)
申请公布日期
2016.06.15
申请号
EP20140833894
申请日期
2014.08.06
申请人
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
发明人
MAHAJAN, NUPAM P.;MAHAJAN, KIRAN N.;LAWRENCE, NICHOLAS J.;LAWRENCE, HARSHANI R.
