发明名称 COMPOUNDS AND METHODS FOR REGULATING INTEGRINS
摘要 A method of treating inflammation, by administering an effective amount of a β2 integrin agonist to a patient, and reducing inflammation. A method of treating cancer, by administering an effective amount of a β2 integrin agonist to a patient, and reducing tumor growth. A method of treating a patient exposed to radiation, by administering an effective amount of a β2 integrin agonist to the patient after radiation exposure, and mitigating the effects of radiation exposure in the patient. A method of preventing effects of radiation, by administering an effective amount of a β2 integrin agonist to the patient prior to radiation exposure, and preventing the effects of radiation exposure on the patient. A method of treating acquired bone marrow failure (BMF), by administering an effective amount of a β2 integrin agonist to a patient. Methods of improving the health of damaged vasculature in a patient and activating β2 integrins.
申请公布号 US2016151336(A1) 申请公布日期 2016.06.02
申请号 US201615040651 申请日期 2016.02.10
申请人 ADHAERE PHARMACEUTICALS, INC. 发明人 Gupta Vineet
分类号 A61K31/427 主分类号 A61K31/427
代理机构 代理人
主权项
地址 Skokie IL US