发明名称 |
SYSTEMS AND METHODS FOR IDENTIFYING COMPOUNDS FROM MS/MS DATA WITHOUT PRECURSOR ION INFORMATION |
摘要 |
Systems and methods are provided for identifying a precursor ion without using any a priori precursor ion information. In one method, a sample is analyzed using a tandem mass spectrometer, producing at least one measured product ion spectrum from a precursor mass-to-charge ratio range. The at least one measured product ion spectrum are received. A subset of measured product ions is selected from the at least one measured product ion spectrum. A list of candidate compounds is created by searching a dictionary of potential compounds that includes one or more predicted product ions for each of the potential compounds using the subset of measured product ions. A candidate compound on the list is selected as the identified compound. In another method, the measured product ions are assumed to correspond to shortened forms of the peptide and a protein database is searched for shortened forms of the peptide. |
申请公布号 |
EP2929339(A4) |
申请公布日期 |
2016.06.01 |
申请号 |
EP20130854471 |
申请日期 |
2013.10.16 |
申请人 |
DH TECHNOLOGIES DEVELOPMENT PTE. LTD. |
发明人 |
TATE, STEPHEN, A.;BONNER, RONALD, F. |
分类号 |
G06F19/00;H01J49/00 |
主分类号 |
G06F19/00 |
代理机构 |
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地址 |
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