| 发明名称 |
3,4-DIAMINOBENZENESULFONAMIDE DERIVATIVES FOR INHIBITING CELL DEATH |
| 摘要 |
The present invention relates to a novel class of compounds having the structure of formula (I) and pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof. These compounds inhibit or reduce the non-apoptotic cell death forms ferroptosis and/or oxytosis rendering them useful for the treatment of various conditions disclosed herein. |
| 申请公布号 |
WO2016075330(A1) |
申请公布日期 |
2016.05.19 |
| 申请号 |
WO2015EP76680 |
申请日期 |
2015.11.16 |
| 申请人 |
VIB VZW;UNIVERSITEIT GENT;UNIVERSITEIT ANTWERPEN |
发明人 |
VANDENABEELE, PETER;VANDEN BERGHE, TOM;AUGUSTYNS, KOEN;JOOSSENS, JURGEN;VAN DER VEKEN, PIETER;HOFMANS, SAM |
| 分类号 |
C07D239/26;A61K31/18;A61K31/4409;A61K31/495;A61K31/535;A61P25/28;C07C311/39;C07C311/40;C07D213/38;C07D295/26 |
主分类号 |
C07D239/26 |
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