GENE SIGNATURE ASSOCIATED WITH TOLERANCE TO RENAL ALLOGRAFT

摘要

The present invention concerns a method for the in vitro diagnosis of a graft tolerant or non-tolerant phenotype, comprising determining from a grafted subject biological sample an expression profile comprising the 20 following genes: TCL1A, MZB1, CD22, BLK, MS4A1, CD79B, BLNK, FCRL2, IRF4, ID3, AKR1C3, HINT1, RFC4, ANXA2R, CD40, FCER2, CTLA4, AKIRIN2, EPS15 and PLBD1; comparing the obtained expression profile with at least one reference expression profile, and determining the graft tolerant or graft non-tolerant phenotype from said comparison.