Neurotrophic peptides for the treatment of tauopathies

摘要

Peptide 6 and in particular, Peptide 021, may be used to treat tauopathies, such as frontotemporal dementia with Parkinsonism linked to chromosome-17 (FTDP-17) tau, corticobasal degeneration, Pick disease, progressive supranuclear palsy, Guam Parkinsonism dementia complex, dementia pugilistica also known as traumatic encephalopathy or traumatic brain injury, ceroid neuronal lipofusinosis, Hallerworden Sptaz disease, Alzheimer's disease, and adults with Down syndrome.

主权项

1. A method of treating a subject having a tauopathy, comprising the step of administering a therapeutic amount of a compound having the sequence Ac-DGGLAG-NH2 (SEQ ID NO: 4).