| 发明名称 |
Novel Super-Resolution Imaging Compositions and Methods Using Same |
| 摘要 |
The invention provides compositions that may be used for imaging intracellular structures. The invention further provides methods of imaging intracellular structures. In certain embodiments, the compositions of the invention include trans-cyclooctene-containing ceramide lipids and tetrazine-containing rhodamine-related dyes. |
| 申请公布号 |
US2016115180(A1) |
申请公布日期 |
2016.04.28 |
| 申请号 |
US201514919216 |
申请日期 |
2015.10.21 |
| 申请人 |
Yale University |
发明人 |
ERDMANN Roman;SHRADER Alanna Schepartz;TOOMRE Derek |
| 分类号 |
C07F7/08;A61K51/04;C07C271/34 |
主分类号 |
C07F7/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A trans-cyclooctene-containing lipid, or a salt, solvate, stereoisomer, or any mixtures thereof, wherein the lipid comprises TCO-LINK-LIPID, wherein TCO is a trans-cyclooctene group, LINK is a bivalent linker, and LIPID is a lipid. |
| 地址 |
New Haven CT US |
