| 摘要 |
PROBLEM TO BE SOLVED: To predict and control change in a biological state.SOLUTION: The amount of expression of molecules in a living body is measured at a specified time interval, measured time-series data are divided into a periodic component, an environmental stimulus response component, and a baseline component, a constant region of the time-series data is identified from variations in the baseline component or from variations in amplitude or a period of the periodic component, and causal relationship between the identified constant regions are identified further. Relationship between variations in internal environment and external environment is identified, and from the identified causal relationship between the constant regions, state change in the living body is estimated. Further, from the identified relationship between the variation in the internal environment and the external environment, disease onset in the living body can be estimated. The molecules can be molecules in blood or molecules in a culture medium.SELECTED DRAWING: Figure 2 |
