Compact multifunctional ligand to enhance colloidal stability of nanoparticles

摘要

A ligand design allows compact nanoparticle materials, such as quantum dots (QDs), with excellent colloidal stability over a wide range of pH and under high salt concentrations. Self-assembled biomolecular conjugates with QDs can be obtained which are stable in biological environments. Energy transfer with these ligands is maximized by minimizing distances between QDs/nanoparticles and donors/acceptors directly attached to the ligands or assembled on their surfaces.

主权项

1. A composition comprising:
a compound is selected from the group consisting of wherein each instance of (A) is independently selected from the group consisting of wherein each respective dashed line represents an amide bond, and wherein each instance of (B) is independently selected from the group consisting of 2-hydroxyethyl, 3-carboxypropyl, 2-carboxyethyl, 2-aminoethyl, and 2-sulfoethyl.