发明名称 |
Use of Polysaccharides for Promotion of Enzymatic Activity |
摘要 |
This disclosure provides methods and compositions for the promotion of enzymatic activity of Target Enzymes, including but not limited to oligosaccharide/polysaccharide enzymes, protein enzymes, polynucleotide enzymes. The methods involve use of a non-naturally occurring polysaccharide (including but not limited HES) for promoting the enzymatic activity of an enzyme in liquid milieu, wherein the concentration of the polysaccharide in the composition comprising the Target Enzyme is from about 0.01% to about 55% w/v. |
申请公布号 |
US2016082090(A1) |
申请公布日期 |
2016.03.24 |
申请号 |
US201514859918 |
申请日期 |
2015.09.21 |
申请人 |
Genzyme Corporation |
发明人 |
Riske Frank;Hayes Michael;Lazarus Gary |
分类号 |
A61K38/47;A61K31/718 |
主分类号 |
A61K38/47 |
代理机构 |
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代理人 |
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主权项 |
1. A composition comprising:
a) a Target Enzyme selected from the group consisting of: an oligosaccharide/polysaccharide enzyme, a protein enzyme, a polynucleotide enzyme, and a lipase, and; b) a non-naturally occurring starch,
wherein the composition comprises from about 0.01% to about 55% w/v of the polysaccharide and wherein the activity of the Target Enzyme has been promoted by the non-naturally occurring polysaccharide. |
地址 |
Cambridge MA US |