发明名称 |
PEPTIDE FOR INDUCING MAST CELL-SPECIFIC APOPTOSIS AND USE THEREOF |
摘要 |
A peptide according to the present invention can perform a function identical or similar to the function of natural CTLA-4 and has an excellent degree of skin penetration due to a small size. The peptide according to the present invention effectively binds to antigen presenting cell surface proteins (CD80 and CD86) to inhibit activity of T cells and thus is capable of inhibiting the expression of inflammatory cytokines (for example, IL-2 and IFN-³). As a result, a composition comprising the peptide according to the present invention exhibits excellent effects in terms of preventing, treating, or improving Th1-mediated immune diseases. Therefore, the superior activity and stability of the peptide according to the present invention can be useful when applied to medicine, quasi-drugs, and cosmetics. |
申请公布号 |
EP2998313(A1) |
申请公布日期 |
2016.03.23 |
申请号 |
EP20130884437 |
申请日期 |
2013.10.25 |
申请人 |
CAREGEN CO., LTD. |
发明人 |
CHUNG, YOUNG JI;KIM, EUN MI;LEE, EUNG-JI;LEE, TAE-HOON;LEE, YOUNG-MIN |
分类号 |
C07K7/08;A61K38/10;A61P37/08 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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