Implantable graft and methods of making same

摘要

The present invention relates to an implantable endoluminal graft having a microporous thin-film covering with a plurality of openings and a structural support element underlying and physically attached to the microporous thin-film covering, the microporous thin-film covering having shape memory properties.

主权项

1. An implantable covered-stent, comprising:
a) a stent including a plurality of cylindrical elements and a plurality of strut members, each fixedly attached to at least one of the plurality of cylindrical elements, wherein at least one of the plurality of strut members is fixedly attached to and interconnects two adjacent cylindrical elements, the stent having a proximal end having at least one enlarged proximal member projecting beyond the proximal end from a first strut member of the plurality of strut members, a distal end having at least one enlarged distal member projecting beyond the distal end from a second strut member of the plurality of strut members, and at least one fenestration disposed between the at least one enlarged proximal member and the at least one enlarged distal member; and b) a metal cover member having a proximal end region, a distal end region, wall surfaces and a plurality of micro-openings passing through the wall surfaces and having an open surface area within the range of 0.5 μm to 150 μm, wherein each of the plurality of micro-openings has an open surface area less than an open surface area of the at least one fenestration, and wherein the proximal end region of said metal cover is fixedly attached by a first thermal method in a first join to the at least one enlarged proximal member, and the distal end region of the metal cover is fixedly attached by a second thermal method in a second join to the at least one enlarged distal member, wherein said metal cover is fixedly attached to the stent only at the enlarged members, wherein the stent and the metal cover member are formed of the same biocompatible metal, and wherein the metal cover at least partially occludes the at least one fenestration to form the implantable covered-stent.