发明名称 Dao1−/−マウスを活用したD−アミノ酸関連疾患の評価・スクリーニング方法
摘要 Disclosed is an evaluation method which can rapidly discriminate a Dao -/- homozygote from a large number of animals produced in a mating experiment between a DAO enzyme deficient mouse and other disease model mice, to rapidly perform a quantitative measurement of the D-amino acids contained in a large number of samples. The invention provides a method for evaluating the effect of a test condition on a mouse tissue, or cultured tissue cells derived from the tissue. The method comprises the steps of: providing a Dao1 -/- mouse or the like; exposing the tissue from the Dao1 -/- mouse or the like, to the test condition; and analyzing the effect of exposing the tissue from the Dao1 -/- mouse or the like, to the test condition.
申请公布号 JP5877862(B2) 申请公布日期 2016.03.08
申请号 JP20140058226 申请日期 2014.03.20
申请人 国立大学法人九州大学;株式会社 資生堂 发明人 浜瀬 健司;財津 潔;三田 真史;芦田 豊;東條 洋介
分类号 C12Q1/68;C12Q1/02;G01N30/88;G01N33/15;G01N33/50;G01N33/53 主分类号 C12Q1/68
代理机构 代理人
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