| 摘要 |
PROBLEM TO BE SOLVED: To provide pharmaceutical formulations having two or more pharmaceutical layers interspersed with one or more intermediate layers, where the pharmaceutical layers include, but are not limited to, pharmaceutical compositions useful for affecting weight loss, suppressing appetite and/or treating obesity-related conditions in individuals.SOLUTION: In one embodiment, a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient included in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine.SELECTED DRAWING: None |
