| 发明名称 |
METHODS FOR OBTAINING RETINAL PROGENITORS, RETINAL PIGMENTED EPITHELIAL CELLS AND NEURAL RETINAL CELLS |
| 摘要 |
A method for in vitro obtaining human retinal progenitors, includes the steps of (i) placing an adherent culture of human pluripotent stem cells in a pro-neural medium; and (ii) maintaining this culture in the pro-neural medium until the appearance of pigmented cells and/or of neuroepithelial-like structures. Additional steps can be performed to obtain RPE cells and/or precursors of the neural retina. |
| 申请公布号 |
US2016060596(A1) |
申请公布日期 |
2016.03.03 |
| 申请号 |
US201414786427 |
申请日期 |
2014.04.25 |
| 申请人 |
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) ;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) |
发明人 |
REICHMAN Sacha;GOUREAU Olivier;SAHEL José-Alain |
| 分类号 |
C12N5/079;C12N5/0793;C12N5/0797 |
主分类号 |
C12N5/079 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for in vitro obtaining human retinal progenitors, comprising the steps of:
(i) placing an adherent culture of human pluripotent stem cells in a pro-neural medium; and (ii) maintaining this culture in said pro-neural medium until the appearance of pigmented cells and/or of neuroepithelial-like structures. |
| 地址 |
Paris FR |
