| 摘要 |
[OBJECT] TO PROVIDE A PHARMACEUTICAL PRODUCT (CHEMOTHERAPEUTIC AGENT) EFFECTIVE IN THE PREVENTION AND TREATMENT OF HYPERLIPIDEMIA, OBESITY, ETC. [SOLVING MEANS] A PHENYLIMIDAZOLE COMPOUND REPRESENTED BY THE FOLLOWING GENERAL FORMULA (1); WHEREIN, R1 REPRESENTS A HYDROGEN ATOM, A PHENYL LOWER ALKYL GROUP OPTIONALLY HAVING A SUBSTITUENT, OR A PYRIDYL LOWER ALKYL GROUP OPTIONALLY HAVING A SUBSTITUENT, AND THE BENZENE RING AND THE PYRIDINE RING ARE OPTIONALLY SUBSTITUTED WITH 1 OR 2 SUBSTITUENTS SELECTED FROM THE GROUP CONSISTING OF HALOGEN ATOMS, CYANO GROUP AND HALOGEN-SUBSTITUTED LOWER ALKYL GROUPS. ONE OF R2 AND R3 REPRESENTS A HYDROGEN ATOM AND THE OTHER REPRESENTS A LOWER ALKOXY GROUP. R4 REPRESENTS A PHENYL GROUP OPTIONALLY HAVING A SUBSTITUENT. R5 AND R6 ARE THE SAME OR DIFFERENT, AND REPRESENT A HYDROGEN ATOM OR A LOWER ALKYL GROUP. R7 AND R8 ARE THE SAME OR DIFFERENT, AND REPRESENT A HYDROGEN ATOM OR A LOWER ALKOXY GROUP. HOWEVER, WHEN R1 REPRESENTS A SUBSTITUTED PHENYL LOWER ALKYL GROUP, R2 REPRESENTS A LOWER ALKOXY GROUP, R3 REPRESENTS A HYDROGEN ATOM, R4 REPRESENTS A PHENYL GROUP OPTIONALLY HAVING A SUBSTITUENT, AND R5 REPRESENTS A HYDROGEN ATOM, R6 IS NOT A HYDROGEN ATOM. |
