| 发明名称 | Solid forms of tacedinaline | ||
| 摘要 | Novel solid forms of tacedinaline (4-(acetylamino)-N-(2-aminophenyl)benzamide), including crystalline tacedinaline Form B, a novel crystalline tacedinaline TFA salt, and amorphous tacedinaline, are disclosed. Pharmaceutical compositions comprising crystalline tacedinaline Form B, the novel crystalline tacedinaline TFA salt, and/or amorphous tacedinaline, and methods of treating various conditions by administering those novel solid forms, are also disclosed. | ||
| 申请公布号 | US9266822(B2) | 申请公布日期 | 2016.02.23 |
| 申请号 | US201414213679 | 申请日期 | 2014.03.14 |
| 申请人 | THE BROAD INSTITUTE, INC. | 发明人 | Holson Edward;Wagner Florence F.;Stahly G. Patrick |
| 分类号 | C07C237/40;A61K31/167;C07C233/80;C07C231/12 | 主分类号 | C07C237/40 |
| 代理机构 | Vedder Price P.C. | 代理人 | Vedder Price P.C. ;Kowalski Thomas J.;Lu Deborah L. |
| 主权项 | 1. A crystalline 4-(acetylamino)-N-(2-aminophenyl)benzamide Form B (tacedinaline Form B). | ||
| 地址 | Cambridge MA US | ||