发明名称 VASCULAR DISRUPTION ANGENT WITH LOW CYTOTOXIC ACTIVITY
摘要 The present application discloses a compound of formula (I), a polymorph, a tautomer, an enantiomer, a stereoisomer, a solvate, or a pharmaceutically acceptable salt thereof for blocking blood stream: wherein each of R1-R6, independently, is R, nitro, nitroso, cyano, azide, isothionitro, OR, OC(O) R, OC (O) OR, OC (O) NRR', SO2R, SO3R, SO2NRR', SR, NRR', NRSO2NR'R", NRSO2R', NRSO3R', NRC (O) R', NRC (O) NR'R", NRC (O) OR', NRC (N) NR'R", C (O) R, C (O) OR, C (O) NRR'; and wherein each of R, R', and R", independently, is hydrogen, halogen, alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, cycloalkenyl, heterocycloalkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl.
申请公布号 WO2016023508(A1) 申请公布日期 2016.02.18
申请号 WO2015CN86871 申请日期 2015.08.13
申请人 SYNCORE BIOTECHNOLOGY CO., LTD;CANCAP PHARMACEUTICAL LTD. 发明人 OU, CHIEN-CHIH;SU, MUH-HWAN;LIU, CHI-LING
分类号 C07D209/12;A61K31/404;A61P35/00;A61P35/02 主分类号 C07D209/12
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